EP-1342: F-18Fluorcholine-PET/CT guide salvage therapy in biochemical failure of prostate cancer

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Treatment failure after primary and salvage therapy for prostate cancer.

BACKGROUND The authors report the likelihood of treatment failure and the outcomes after salvage therapy among men with prostate cancer who initially either received external-beam radiation therapy (EBRT) or underwent radical prostatectomy (RP). METHODS Using a national disease registry, the Cancer of the Prostate Strategic Urological Research Endeavor (CaPSURE) database, 5277 men with prosta...

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Salvage Therapy for Prostate Cancer

Biochemical recurrence after treatment of prostate cancer occurs in 30–50 % of patients. Confirming that recurrence is localized to the pelvis is challenging as PSA is nonspecific and imaging modalities are imperfect in identifying location of recurrent disease. Salvage therapy after radical prostatectomy is limited to external beam radiotherapy and androgen-deprivation therapy. After radiothe...

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Prostate-specific antigen decline during salvage radiation therapy following prostatectomy is associated with reduced biochemical failure.

PURPOSE To evaluate the prognostic value of prostate-specific antigen (PSA) decline during salvage radiation therapy (SRT) after prostatectomy. METHODS AND MATERIALS We reviewed an institutional database and identified all prostate cancer patients who were treated with SRT between the years 2003 and 2010, had at least 1 PSA measurement during their SRT course, and had no history of androgen d...

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Long-term Outcome of Prostate Cancer Patients Who Exhibit Biochemical Failure Despite Salvage Radiation Therapy After Radical Prostatectomy.

OBJECTIVES Salvage radiation therapy (SRT) is an effective treatment for recurrent prostate cancer (PCa) after radical prostatectomy. We report the long-term outcome of men who developed biochemical recurrence (BCR) after SRT and were treated >14 years ago. METHODS In total, 61 patients treated with SRT from 1992 to 2000 at our institution were identified. Survival was calculated by Kaplan-Me...

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Salvage Radiation Therapy for Biochemical Failure Following Radical Prostatectomy.

BACKGROUND Radiotherapy to the prostate bed is used to eradicate residual microscopic disease following radical prostatectomy for prostate cancer. Recommendations are based on historical series. OBJECTIVES To determine outcomes and toxicity of contemporary salvage radiation therapy (SRT) to the prostate bed. METHODS We reviewed a prospective ethics committee-approved database of 229 patient...

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ژورنال

عنوان ژورنال: Radiotherapy and Oncology

سال: 2016

ISSN: 0167-8140

DOI: 10.1016/s0167-8140(16)32592-0